Assistant Research Scientist
Purdue University
Department of Biological Sciences, Purdue University
Dr. Genki Terashi is an Assistant Research Scientist at the Kihara Laboratory, Department of Biological Sciences, Purdue University. He specializes in computational structural biology, with a focus on cryo-electron microscopy (cryo-EM)-based protein structure modeling and validation.
Dr. Terashi has led or contributed to the development of numerous computational tools widely used in the cryo-EM community. These include MAINMAST for de novo backbone tracing, VESPER for map alignment, CryoREAD for nucleic acid modeling, and DeepMainmast, a deep learning-based modeling protocol. Most recently, he co-developed DiffModeler, which applies diffusion models to enhance large-scale structure modeling from low-resolution EM maps.
In addition to modeling, he developed the DAQ score, a deep learning metric for evaluating map–model compatibility, and EM-GAN, which enhances EM maps using generative networks. His methods are known for improving the accuracy, resolution, and interpretability of protein and nucleic acid models derived from cryo-EM data.